Natsume has been busy, navigating between humans and Yokai when he coincidentally reunites with an old classmate, Yuki. The reunion brings back painful memories of a certain Yokai. Meanwhile, Natsume also becomes acquainted with Yorie Tsumura, a woman in the memories of a Yokai whose name Natsume had returned. Yorie knows much about Reiko, and now lives a peaceful life with her only son, Mukuo. Interacting with this family is comforting for Natsume, but a mysterious Yokai has been lurking in their town. On the way back from investigating, a “Yokai seed” that had latched itself to Nyanko-Sensei drops into the Fujiwara Family’s garden and grows overnight into a fruit tree. When Nyanko-Sensei eats a fruit that is somewhat shaped like himself, he suddenly splits into three!