"Every body needs a hero."

2001

1h 35m

6.5(1063 votes)

Adventure

Animation

Action

Comedy

Family

Science Fiction

Overview

A white blood cell policeman, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.

Where to Watch

Buy

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Links & Resources

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Social & External

IMDb

Production Companies

Videos & Trailers

5 videos

Cast & Crew

86 members

Acting

Chris Rock

Osmosis Jones (voice)

Acting

Laurence Fishburne

Thrax (voice)

Acting

David Hyde Pierce

Drix (voice)

Acting

Brandy Norwood

Leah (voice)

Acting

Elena Franklin

Shane Detorre

Acting

Bill Murray

Frank Detorre

Acting

William Shatner

Mayor Phlegmming (voice)

Directing

Ron Howard

Tom Colonic (voice)

Acting

Kid Rock

Kidney Rock (voice)

Acting

Molly Shannon

Mrs. Boyd

Acting

Chris Elliott

Bob

Acting

Jonathan Adams

Officer Tom (voice)

Acting

Carlos Alazraqui

Spanish Germ (voice)

Acting

Keith Anthony

Additional Character Voices (voice)

No Image

Acting

Eddie Barth

Conductor (voice)

Acting

Sally Brooks

Additional Character Voices (voice)

Acting

Rodger Bumpass

Joe Cramp / Announcer for Nerve News Network (voice)

Acting

Michael Carven

Additional Character Voices (voice)

No Image

Acting

Paul Christie

Dan Matter / Germ (voice)

No Image

Acting

Janis Dardaris

Additional Character Voices (voice)

Acting

Wendy Dillon

Additional Character Voices (voice)

No Image

Acting

Antonio Fargas

Chill the Flu Shot (voice)

Acting

Eddie Frierson

Frank Police Department Officer (voice)

Acting

Donald Fullilove

Doughnut (voice)

Acting

Jackie Gonneau

Additional Character Voices (voice)

Acting

Shannon Gregory

Additional Character Voices (voice)

No Image

Acting

Richard Steven Horvitz

Additional Character Voices (voice)

Acting

Rif Hutton

Charlie (voice)

Acting

Art Kimbro

Additional Character Voices (voice)

No Image

Acting

Joyce Kurtz

Additional Character Voices (voice)

No Image

Acting

Anne Lockhart

Female Red Blood Cell (voice)

Acting

Sherry Lynn

Trudy (voice)

Acting

Danny Mann

Musician Cell (voice)

Acting

Mickie McGowan

Brain Librarian (voice)

Acting

Kenny Olson

Kidney Rock Band (voice)

No Image

Acting

Jason Krause

Kidney Rock Band (voice)

No Image

Acting

Joe C.

Kidney Rock Band (voice)

No Image

Acting

Stefanie Eulinberg

Kidney Rock Band (voice)

No Image

Acting

Jimmie Bones

Kidney Rock Band (voice)

No Image

Acting

Uncle Kracker

Kidney Rock Band (voice)

No Image

Production

Joel Silver

Police Chief (voice) (uncredited)

Writing

David Ossman

Scabies (voice) (uncredited)

No Image

Acting

John Melendez

Artie (voice)

Acting

Héctor Mercado

Additional Character Voices (voice)

Acting

Paul Pape

Male Red Blood Cell #2 (voice)

Acting

Marilyn Pasekoff

Additional Character Voices (voice)

No Image

Acting

Chris Phillips

Firefighter Doug (voice)

Production

Lynne Redding

Additional Character Voices (voice)

No Image

Acting

Al Rodrigo

Frank Police Department Walkie Talkie (voice)

Acting

Herschel Sparber

Bruiser (voice)

Acting

Doug Stone

Police Officer Jamie (voice)

No Image

Acting

Steve Susskind

Mob Boss Germ (voice)

No Image

Acting

Keri Tombazian

Additional Character Voices (voice)

Acting

Paul Tuerpe

Additional Character Voices (voice)

Acting

Robert Wisdom

Big Germ (voice)

Acting

Danny Murphy

Zookeeper Superintendent

Acting

Jack McCullough

Zookeeper

No Image

Acting

Will Dunn

Oyster Boy

No Image

Acting

Jackie Flynn

School Janitor

Acting

Kelsey Jordan

Bus Girl #1

No Image

Acting

Abe Farrelly

Bus Girl #2

Acting

Jesse Peter

Laughing Boy

No Image

Acting

John-Eliot Jordan

Pea Soup Manager

No Image

Acting

Nancy Byers

Pea Soup Supervisor

No Image

Acting

Kevin J. Flynn

Docky's Clamshack Waiter

Acting

Sean Gildea

Dreamy Photographer

Acting

Kathryn Frick

Nurse #1

No Image

Acting

Nikki Tyler-Flynn

Nurse #2

Acting

Elizabeth Jordan

Nurse #3

No Image

Acting

Zen Gesner

ER Doctor #1

Writing

Marc Hyman

ER Doctor #2

No Image

Writing

Zak Penn

ER Doctor #3

Acting

Diane Conrad

Zoo Visitor or Staff

No Image

Acting

Judith Conrad

Zoo Visitor or Staff

No Image

Visual Effects

Thomas Jordan

The Zoo Visitor or Staff

No Image

Art

Sydney J. Bartholomew Jr.

Zoo Visitor or Staff

No Image

Acting

Erica Johnson

Zoo Visitor or Staff

No Image

Acting

Bo Cleary

Pea Soup Staff

No Image

Acting

Bruce McIntyre

Pea Soup Staff

No Image

Costume & Make-Up

Colleen O'Donnell

Docky's Clamshack

No Image

Acting

Docky

The Bikini Gang

No Image

Acting

Joe Murphy

The Bikini Gang

No Image

Acting

Brian Mone

Police Officer

No Image

Acting

Sean Fitzgerald

Police Officer

No Image

Acting

Grace Costa

ER Nurse

No Image

Acting

Emily O’Donnell

School Girl

No Image

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