CinemaOSMovie · 2010 · 1h 44m · R
Splice

She's not human...not entirely.

59%(2,545)IMDbHorrorScience Fiction

Elsa and Clive, two rebellious young scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators — only to have that bond turn deadly.

Directed byVincenzo Natali

Play
Status
Released
Runtime
1h 44m
Language
EN
Released
June 3, 2010
Budget
$26,000,000
Studios
Copperheart EntertainmentGaumontSenator Film

Watch the

Trailers & teasers

8 videos
Trailer

Trailer

TV Spot # 5

TV Spot # 5

TV Spot # 6

TV Spot # 6

TV Spot #4

TV Spot #4

TV Spot #5

TV Spot #5

TV Spot #1

TV Spot #1

TV Spot #2

TV Spot #2

TV Spot #3

TV Spot #3

Featuring

Cast & crew

8 credited
Starring
Adrien Brody

Adrien Brody

Clive Nicoli

Sarah Polley

Sarah Polley

Elsa Kast

Delphine Chanéac

Delphine Chanéac

Dren

Brandon McGibbon

Brandon McGibbon

Gavin Nicoli

Simona Măicănescu

Simona Măicănescu

Joan Chorot

David Hewlett

David Hewlett

William Barlow

Abigail Chu

Abigail Chu

Child Dren

Doug Hicton

Lab tech (uncredited)

Creative team
Directed by
Vincenzo Natali
Vincenzo Natali
Written by
Vincenzo Natali
Vincenzo Natali
Antoinette Terry Bryant
Produced by
Steven Hoban
Steven Hoban

Keep watching

More like this

I Married a Vampire4.8

I Married a Vampire

1987 · Film

Heart of a Dog7.9

Heart of a Dog

1988 · Film

Amphibian Man6.8

Amphibian Man

1962 · Film

Rabbits6.7

Rabbits

2002 · Film

I Spit on Your Grave6.5

I Spit on Your Grave

2010 · Film

Twice-Told Tales6.2

Twice-Told Tales

1963 · Film

Esperia8.5

Esperia

2025 · Film

Haunted Villa6.5

Haunted Villa

1981 · Film

Krakatit6.5

Krakatit

1948 · Film

Poison6.0

Poison

1991 · Film

MadS6.4

MadS

2024 · Film

The Giant Behemoth5.8

The Giant Behemoth

1959 · Film

I Was a Teenage Werewolf4.8

I Was a Teenage Werewolf

1957 · Film

The H-Man5.8

The H-Man

1958 · Film

And Now the Screaming Starts!5.9

And Now the Screaming Starts!

1973 · Film

Night of the Bloody Apes5.5

Night of the Bloody Apes

1969 · Film

The NeedyMonster

The NeedyMonster

2025 · Film

The Night Caller5.6

The Night Caller

1965 · Film

Devil Returns6.0

Devil Returns

1982 · Film

Picked for you

Recommended movies

The Kindred6.0

The Kindred

1987 · Film

Species6.0

Species

1995 · Film

The Fly7.4

The Fly

1986 · Film

Demon Seed5.9

Demon Seed

1977 · Film

Deep Blue Sea6.0

Deep Blue Sea

1999 · Film

Cat People6.0

Cat People

1982 · Film

The Creeping Flesh5.9

The Creeping Flesh

1973 · Film

Man-Made Monster6.1

Man-Made Monster

1941 · Film

Alligator6.0

Alligator

1980 · Film

Sleepwalkers6.1

Sleepwalkers

1992 · Film

Frankenstein Must Be Destroyed6.3

Frankenstein Must Be Destroyed

1969 · Film

Hollow Man6.0

Hollow Man

2000 · Film

Crimes of the Future6.0

Crimes of the Future

2022 · Film

Assimilate6.3

Assimilate

2019 · Film

Alien: Covenant6.2

Alien: Covenant

2017 · Film

Clayface7.6

Clayface

2026 · Film

The Brood6.7

The Brood

1979 · Film

Alien: Romulus7.2

Alien: Romulus

2024 · Film

The Thing6.3

The Thing

2011 · Film

Eraserhead7.3

Eraserhead

1977 · Film